Haloarchaeal virus morphotypes

Monitoring Physiological Changes in Haloarchaeal Cell during Virus Release.

The slow rate of adsorption and non-synchronous release of some archaeal viruses have hindered more thorough analyses of the mechanisms of archaeal virus release. To address this deficit, we utilized four viruses that infect Haloarcula hispanica that represent the four virion morphotypes currently known for halophilic euryarchaeal viruses: (1) icosahedral internal membrane-containing SH1; (2) i...

HaloWeb: the haloarchaeal genomes database

BACKGROUND Complete genome sequencing together with post-genomic studies provide the opportunity for a comprehensive 'systems biology' understanding of model organisms. For maximum effectiveness, an integrated database containing genomic, transcriptomic, and proteomic data is necessary. DESCRIPTION To improve data access and facilitate functional genomic studies on haloarchaea in our laborato...

The haloarchaeal chromosome replication machinery.

The powerful combination of genetic and biochemical analysis has provided many key insights into the structure and function of the chromosomal DNA replication machineries of bacterial and eukaryotic cells. In contrast, in the archaea, biochemical studies have dominated, mainly due to the absence of efficient genetic systems for these organisms. This situation is changing, however, and, in this ...

Reconstruction, Modeling & Analysis of Haloarchaeal Metabolic Networks

Horizontal Gene Transfer, Dispersal and Haloarchaeal Speciation

The Halobacteria are a well-studied archaeal class and numerous investigations are showing how their diversity is distributed amongst genomes and geographic locations. Evidence indicates that recombination between species continuously facilitates the arrival of new genes, and within species, it is frequent enough to spread acquired genes amongst all individuals in the population. To create perm...